WEBINAR: Evidence-Based Strategy in the Prevention of Complications due to Retained Blood

October 20, 2023 at 11:00 AM Eastern/8:00 AM Pacific

Industry experts will discuss the latest research, evidence-based strategies, and best practices in preventing complications associated with retained blood to help enhance patient care and safety for a significant impact in healthcare settings.



Bleeding after heart surgery: Better out than in!

All patients bleed in the early hours after heart surgery. The post-operative blood shed into the chest is drained through chest tubes and collected in drainage blood-clotcanisters. For some this is just a few hundred cc’s and then it stops. For others it can be more than a liter. In these early hours after surgery great efforts are taken to support the patient until coagulation is restored and bleeding subsides. In recent era, the potential for bleeding has increased because of more liberal use of antiplatelet medications like Plavix, as well as more complex and often redo procedures. Some patients bleed more because the operation is urgent and the patient is in shock, while others bleed quite unexpectedly when coagulation problems ensue without apparent cause. And occasionally, patients bleed because of a surgical source that needs re-suturing for reinforcement.(1) Whatever the cause, worse outcomes and costs are directly tied to the volume of bleeding, and even what are seemingly small volumes can cause problems.(2, 3)

Where the post-operative blood ends up, however, can make a drastic difference in outcomes. Cardiac caregivers have long recognized the importance of bleeding OUT, versus bleeding IN. This is why surgeons put in chest tubes to drain the blood OUT from around the heart and lungs while coagulation is restored in the early hours after cardiothoracic surgery. During this time the blood undergoes a phase change from liquid to solid as the coagulation system kicks back in. Keeping the shed blood flowing OUT through the chest tubes during that phase can be a challenge as chest tubes are prone to clog and obstruct. Nurses often strip and tap chest tubes tubes to try to break up the clots that block the tubes to help the blood get OUT. But even with the best efforts, studies show that chest tubes clog in 36% of patients, preventing adequate evacuation of the shed blood. In these patients, the shed blood can stay IN rather than draining OUT. When blood stays IN, it can manifest as Retained Blood Complex (RBC)

This is why caregivers take so many efforts to make sure the patient shed blood is drained OUT. When the bleeding comes OUT, the caregiver can measure the amount and know when the patient is beginning to coagulate. When the bleeding comes OUT, the caregiver knows when it stops. When the bleeding comes OUT, the patient can avoid the cardiac and respiratory compromise that comes with blood accumulating around the heart and lungs in the early hours after surgery. When the shed blood comes OUT, clot does not form around the heart and lungs and develop into pleural and pericardial effusions.  When the bleeding comes OUT, complications from retained blood can be minimized and perhaps even readmissions avoided.

Studies have shown that the key to helping the patient maximally drain shed blood in the early hours after surgery is having patent chest drainage catheters.(4, 5) PleuraFlow ACT is the only regulatory-cleared device that enables clinicians to proactively maintain chest drainage catheter patency during this critical time. You may not be able to control when or why patients bleed, but you can significantly influence if they bleed OUT rather than IN.


1. Loor, G, Vivacqua, A, Sabik, J.F., Li, L, Hixson, E.D., Blackstone, E.H., Koch, C.G. 2013. Process improvement in cardiac surgery: Development and implementation of a reoperation for bleeding checklist. J of Thorac and Cardiovasc Surg. 146(5): 1028-1032.

2. Dixon, B., Santamaria, J.D., Reid, D., Collins, M., Rechnitzer, T., Newcomb, A.E., Nixon, I., Yii, M., Rosalion, A., and Campbell, D.J. 2012. The association of blood transfusion with mortality after cardiac surgery: cause or confounding? Transfusion.

3. Christensen, M.C., Dziewior, F., Kempel, A., and von Heymann, C. 2012. Increased chest tube drainage is independently associated with adverse outcome after cardiac surgery. J Cardiothorac Vasc Anesth 26:46-51.

4. Shiose, A.; Takaseya, T.; Fumoto, H.; Arakawa, Y.; Horai, T.; Boyle, E. M.; Gillinov, A. M.; Fukamachi, K. “Improved drainage with active chest tube clearance.” Interactive CardioVascular and Thoracic Surgery 10 (5): 685–688.

5. Arakawa, Yoko; Shiose, Akira; Takaseya, Tohru; Fumoto, Hideyuki; Kim, Hyun-Il; Boyle, Edward M.; Gillinov, A. Marc; Fukamachi, Kiyotaka. “Superior Chest Drainage With an Active Tube Clearance System: Evaluation of a Downsized Chest Tube.” The Annals of Thoracic Surgery 91 (2): 580–583